Endocrine Abstracts

Glucose-dependent insulinotropic peptide (GIP) contributes to incretin effect of insulin secretion which is impaired in type 2 diabetes mellitus. The aim of this study was to develop a simple meal test for evaluation of GIP secretion and action and to examine GIP changes in type 2 diabetic patients. Seventeen type 2 diabetic patients, 10 obese non-diabetic and 17 non-obese control persons have been examined before and after 30, 60 and 90 min stimulation by meal test. In a mixe...